STUDY OF SERUM URIC ACID LEVEL AS A PROGNOSTIC FACTOR IN ACUTE ISCHEMIC STROKE - A HOSPITAL BASED STUDY

Dr. Raghunandan Meena; Dr. Khushala Ram Choudhary

Volume : IX, Issue : I, January - 2020

STUDY OF SERUM URIC ACID LEVEL AS A PROGNOSTIC FACTOR IN ACUTE ISCHEMIC STROKE - A HOSPITAL BASED STUDY

Dr. Raghunandan Meena, Dr. Khushala Ram Choudhary

Abstract :

Background –SUA level is found to be associated with cardiovascular disease and DM. SUA role is controversial in stroke and need to be elucidated further. Aim– To determine the importance of SUA as a prognostic factor in AIS patients. Methods– A prospective study carried out over one year, including 72 cases of AIS. SUA levels were done on Day 1 and Day 4 and were statistically analyzed. Results– 26.39% of stroke patients had SUA ≥ 7 mg/dl. In AIS, hyperuricemia had statistically significant association with hypertension and CAD with a p value of 0.02 and 0.044 respectively. Difference in mean MRS score at day one and day four in two groups having SUA level <7 and ≥ 7mg/dl was not significant at day one (p=0.119) but it was found significant at day four (p=0.022) indicating poor improvement or prognosis among hyperuricemic group. Conclusions– SUA can be used for risk stratification and as an indicator of poor prognosis in acute ischemic stroke.