Study of Left Ventricular Function in Chronic Obstructive Pulmonary Disease and its Correlation

Dr. Ranjeet Badole

Volume : VIII, Issue : I, January - 2019

Study of Left Ventricular Function in Chronic Obstructive Pulmonary Disease and its Correlation

Dr. Ranjeet Badole

Abstract :

Background: Chronic Obstructive Pulmonary Disease (COPD) has considerable effects on cardiac function, including those of the right ventricle, left ventricle and pulmonary blood vessels. Most of the mortality in COPD is related to heart3. Aim: To assess the functional changes of left ventricle in patients with COPD with normal Right Ventricular Function and to find out the correlation between the left ventricular changes and the severity of COPD. Materials &Methods: 51 COPD patients with unknown severity were taken into the study. Patients were categorized into four groups based on GOLD Staging. Echocardiographic assessment of right ventricular and left ventricular function were done using Ejection fraction, diastolic function, Tei index, Global function and Respiratory variation. Results: A total of 51 patients were recruited in our study, among them 47 patients were Male and 4 patients were Female. Right atrial enlargement and Right Axis Deviation were more common in patients with severe and very severe COPD. Pulmonary hypertension was present in 33.3% (2/6), 28.6% (4/14), 82.3% (14/17) and 71.4% (10/14) cases of mild, moderate, severe and very severe obstruction respectively (P<0.005). Right ventricular Function was normal in all Patients. Left ventricular ejection fraction also was preserved in all patients. When Compared with COPD severity, diastolic dysfunction of Left ventricle was noted in patients with Severe (6/17 patients) and Very Severe COPD (10/14 patients). Left ventricular filling is affected in all group of COPD, it is more when severity increases (Severe COPD – 6/17 patients, Very COPD–9/14 patients). Conclusion: Left ventricular ejection fraction is preserved in all group of COPD patients those who are having normal RV function. But Left ventricular filling is affected in patients with severe COPD without affecting ejection fraction