Volume : VII, Issue : X, October - 2018
Spectrum of Complications in haemoglobinopathies-a study in central India
Khaire Prabha B, Dahyalkar Amol A, Babasaheb Suroshe, Smita Mundada
Abstract :
INTRODUCTION:
Thalassemias are hereditary hemolytic anemia with autosomal recessive inheritance characterized by inability to produce one or more globin chains forming hemoglobin molecule.
MATERIAL AND METHODS:
Prospective observational study conducted at tertiary care hospital from January 2015 – November 2016.Total187 patients of haemoglobinopathies satisfying the inclusion and exclusion criteria were enrolled. Detailed histories with clinical examination were noted in preformed structural proforma.
Results
Complication rates were significantly higher among thalassemia major patients compared to other haemoglobinopathy. Stunting in thalassemia major group160 (85.5%), sickle cell disease 11(91.6%),splenomegaly was noticed in 141(75.4%).Cardiac complication 16(8.5%), most common complication was Congestive cardiac failure 10 (5.8%) cases, followed by Early transfusion reaction in 9 (5.2%), and infection (sepsis and onchopneumonia) was seen in 6(3.5%).
CONCLUSION: Complication were Stunting, splenomegaly, Congestive cardiac failure, Early transfusion reaction, and Infection (sepsis and onchopneumonia) seen.
Keywords :
Article:
Download PDF
DOI : https://www.doi.org/10.36106/paripex
Cite This Article:
Khaire Prabha B, Dahyalkar Amol A, Babasaheb Suroshe, Smita Mundada, Spectrum of Complications in haemoglobinopathies-a study in central India, PARIPEX‾INDIAN JOURNAL OF RESEARCH : Volume-7 | Issue-10 | October-2018
Number of Downloads : 171
References :
Khaire Prabha B, Dahyalkar Amol A, Babasaheb Suroshe, Smita Mundada, Spectrum of Complications in haemoglobinopathies-a study in central India, PARIPEX‾INDIAN JOURNAL OF RESEARCH : Volume-7 | Issue-10 | October-2018