Primary embryonal mandibular rhabdomyosarcoma with multiple metastasis in a young girl

Shilpi Gangwar; Hari Ram; Dr Pawan Goyal; Jagdish Gamit

Volume : VII, Issue : V, May - 2018

Primary embryonal mandibular rhabdomyosarcoma with multiple metastasis in a young girl

Shilpi Gangwar, Hari Ram, Dr Pawan Goyal, Jagdish Gamit

Abstract :

An emyonal rhabdomyosarcoma (ERMS) is a most common , primitive, malignant, soft tissue sarcoma in children under 15 yrs of age. It is considered to result from malignant transformation of primitive mesenchymal cells. Although it has a predominance for head and neck region , it is found less often in oral cavity. Here we report a case of ERMS of mandible in a 13 year old young girl. Clinical and pathologic findings are described , which were confirmed by histochemical and immunohistochemical stains.Three cycles of chemotherapy resulted in over 50% reduction in size of the mass. However, increase in size was noted subsequent to completion of therapy . In nine months, the patient developed multiple metastases, radionuclide bone scan showed increased tracer uptake on left side of mandible in angle, ramus region, and right pubis region . Patient died despite chemotherapy .