Observations of serum magnesium level in relation to complications and severity of chronic renal failure

Dr. Himanshu Kumar

Volume : VIII, Issue : III, March - 2019

Observations of serum magnesium level in relation to complications and severity of chronic renal failure

Dr. Himanshu Kumar

Abstract :

Chronic kidney disease forms large pool of patients in the world. Cardiovascular disease is the leading cause of mortality and morbidity in patients with chronic kidney disease, which is partly explained by the fact that 40–70% of patients receiving dialysis have significant coronary artery disease. Recent clinical studies have shown that lower serum magnesium(Mg) levels are associated with vascular calcification and cardiovascular mortality among patients with end–stage renal disease(ESRD). AIMS & OBJECTIVES OF THE STUDY was to study the serum magnesium levels in chronic renal failure & to detect correlation if any of serum magnesium with clinical feature , severity of CRF on various parameters. In this study clinical significance of serum magnesium levels in patients with CRF and its correlations with the sodium, potassium and calcium were studied There was significant increase in serum magnesium level in patients with CRF,Serum magnesium level increased with duration of the illness in CRF patients,Serum magnesium level was higher in the patients with adycardia,Serum magnesium level was higher in patients with uremic encephalopathy,There was positive correlation between serum magnesium levels and blood urea, serum magnesium and serum creatinine& serum magnesium and serum potassium levels,There was negative correlation between serum magnesium and serum calcium level in CRF patients,No correlation was found between serum magnesium and serum sodium.Serum magnesium is a worthwhile tool in assessing duration of disease morbidity and mortality in patients with chronic renal failure. Its estimation may help in evaluating conservative treatment and dialysis in CRF patients.