Volume : VII, Issue : IV, April - 2018

Merkel cell carcinoma of the eyelid: a case report

Zornitsa I. Zlatarova

Abstract :

Merkel cell carcinoma is aggressive neuroendocrine tumor that extremely rare affects the eyelids.

Purpose: To present a case of a 54–years old woman with Merkel cell carcinoma of the eyelid. 

Methods: Standard ophthalmic examination,surgical excision of the tumor and histopathological, and immunohistochemical examination.

Results: Patient presents with solid pink–violet lesion in left upper eyelid. Histopathological examination shows combined Merkel cell and squamous cell carcinoma. Three months after eyelid surgery PET/CT shows suspicious neck lymph nodes in both sides. Five months after surgery left sideregional cervical lymph nodes excision was performed. Histopathological examination found metastases associated with neurendocrin carcinoma in 15 lymph eyelid nodes and perinodal soft tissues. Patient dies one year after eyelid surgery as a consequence of metastases of primary eyelid tumor, despite surgical and radiation therapy.

Conclusions:Presented case confirms possibility for combination of Merkel cell with squamous cell carcinoma and the aggressive clinical course of these tumors.  Merkel cell carcinoma very rare arises from eyelid but is of significance to the ophthalmologists because of its life–threatening potential.

Article: Download PDF    DOI : https://www.doi.org/10.36106/paripex  

Cite This Article:

Zornitsa I. Zlatarova, Merkel cell carcinoma of the eyelid: a case report, PARIPEX‾INDIAN JOURNAL OF RESEARCH : Volume-7 | Issue-4 | April-2018

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