EVALUATION OF THYROID HORMONES IN POLYCYSTIC OVARIAN SYNDROME

Dr.M.Sangamithra; Dr.A.Padma Vijayasree

Volume : VII, Issue : IX, September - 2018

EVALUATION OF THYROID HORMONES IN POLYCYSTIC OVARIAN SYNDROME

Dr. M. Sangamithra, Dr. A. Padma Vijayasree

Abstract :

Background: Polycystic ovarian syndrome (PCOS) is the most common endocrinopathyof reproductive age affecting 5% to 10% of women worldwide and is a leading cause of infertility . PCOS is closely associated with hypothyroidism and is risk factor for ovarian malfunction and infertility.

Objectives: To estimate and compare thyroid hormones in PCOS patients and healthy controls.

Materials and methods: A case control study was conducted on 100 individuals (50 PCOS patients and 50 healthy controls). Serum TSH, freeT3, free T4 were estimated by Chemiluminescence assay (CLIA).

Results: Serum TSH levels were significantly increased in cases whereas free T3, free T4 were decreased in cases as compared to controls.

Conclusion: PCOS is associated with hypothyroidism. Evaluation of thyroid hormones may help in preventing complications like ovarian dysfunction and infertility.