EFFECT OF TOPICAL APPLICATION OF HONEY IN RADIATION INDUCED MUCOSITIS IN HEAD AND NECK CANCER PATIENTS

Dr. B. Padmavathi

Volume : VII, Issue : III, March - 2018

EFFECT OF TOPICAL APPLICATION OF HONEY IN RADIATION INDUCED MUCOSITIS IN HEAD AND NECK CANCER PATIENTS

Dr. B. Padmavathi

Abstract :

Background : The Head and Neck forms the 7th most common cancer world wide . They are the most common cancer in developing countries in South east Asia. Head and Neck more common in males compared to females. Radiation therapy plays a significant role as a primary treatment in early stage cancers and in the Adjuvant treatment of later stage Head and Neck cancers. In this study the patients were belongs to all subsidies of Head and Neck cancers irrespective of stage expect for Metastasis. Aims and Objective : Aims : 1. To know the effect of topical application of honey on the onset of mucositis in Head and Neck cancer patients receiving concurrent chemo radiation. 2. To assess the effect of topical application of honey on severity of mucositis in Head and Neck cancer patients receiving concurrent chemo radiotherapy. Methods : Total 56 Head and Neck cancer patients who were to receive concurrent chemo radiotherapy treatment were recruited in this study. Out of 27 were allocated in study group and remaining 29 were allocated into control group. Study group received honey for topical application along with chemo radiotherapy where as control group received chemo radio therapy. Results: Two types of mocositis seen in this study : 1. On set of radiation induced of mocositis : Most of the patients in this study group developed mucositis (92.6%) by the end of 13th fraction. Majority of patients (51.7%) in control group developed mucositis in 10th fraction. 2. Severity of Radiation induced Mucositis : Severity of mucositis was less in study group compared to control group. Conclusion : Topical application of honey reducing in the onset as well as severity of radiation induced mucositis in patients receiving radiation to Head and Neck cancers.