COMPARISON OF TOTAL AND DIFFERENTIAL LEUCOCYTE COUNT IN DIFFERENT TRIMESTERS OF PREGNANCY AND AFTER DELIVERY

Dr. HEENA KAURANI; Dr. RITU GUPTA; Dr.NIDHI GOLECHA

Volume : VIII, Issue : V, May - 2019

COMPARISON OF TOTAL AND DIFFERENTIAL LEUCOCYTE COUNT IN DIFFERENT TRIMESTERS OF PREGNANCY AND AFTER DELIVERY

Dr. Heena Kaurani, Dr. Ritu Gupta, Dr. Nidhi Golecha

Abstract :

Pregnancy is characterized by changes in many physiological and hematological parameters. There is an increase in white blood cell count arising mainly from neutrophilia and to a lesser extent, monocytosis. This neutrophilia is attributed to physiological stress and it is known to increase with gestational age. The increase in the number of neutrophils is due to decrease in the activity of their apoptosis mechanism during pregnancy. During labour, there is further delayed in neutrophils apoptosis which leads to further increase of the WBC counts after normal vaginal delivery. It is important to note that leukocytosis even with mild left shift and some toxic granulations may not necessarily indicate an infection in women during pregnancy and in immediate puerperium. The aim of this study was to assess the changes in total and differential leukocytes counts in pregnancy in different trimesters and after delivery in comparison with non–pregnant controls. Our study shows a significant increase in WBC, Neutrophil, Lymphocyte and Monocyte counts with increase in gestational age and after delivery but Eosinophil and Basophils do not show any significant correlation with pregnancy.