Comparative evaluation of the antibacterial efficacy of calcium hydroxide as an intracanal medicament and combination of calcium hydroxide with food preservatives and proton pump

Dr Suman Kar; Dr. Swarupananda Bera; Dr. Debjyoti Karmakar

Volume : IX, Issue : I, January - 2020

Comparative evaluation of the antibacterial efficacy of calcium hydroxide as an intracanal medicament and combination of calcium hydroxide with food preservatives and proton pump

Dr Suman Kar, Dr. Swarupananda Bera, Dr. Debjyoti Karmakar

Abstract :

Aim: To evaluate the antimicrobial effcacy of nisin and calcium hydroxide with and without pantoprazole against Enterococcus faecalis. Materials and methods: The antibacterial effect of the following experimental groups as intracanal medicaments(Group I— Ca(OH)2, Group II – Ca(OH)2 + Nisin, Group III – Ca(OH)2 + Nisin + PPI, Group IV— Ca(OH)2 + PPI) was evaluated using the agar diffusion test for a time period of 24 hours. The minimum inhibitory concentration (MIC) against E. Faecalis were also determined. Statistical analysis was performed using Kruskal–Wallis Test and chi–square test. Results: In this study the antibacterial efficacy is detected by the formation of the zone of inhibition around the wells inoculated with the experimental groups. Groups I, II, III and IV showed inhibitory zones. In group IV the maximum diameter of 22 mm is obtained . The MIC values for the experimental groups I, II, III, and IV were 0.45%,0.2mg/ml,0.45%+0.03mg/ml, ≤0.01% respectively. Conclusion: The antimicrobial efficacy of omeprazole (PPI) combined with calcium hydroxide shows the maximum zone of inhibition and according to this study; this combination shows the most potent intracanal medicaments.