Volume : VII, Issue : IV, April - 2018

Bronchodilator reversibility in chronic obstructive pulmonary disease

Dr. Ajithkumar. C. S.

Abstract :

Background:  Although airflow obstruction in COPD is not fully reversible, patients can still exhibit clinically significant onchodilator reversibility.  This study assessed onchodilator reversibility in COPD

Materials and methods:  Spirometric parameters were measured before and after inhaled 400 µg salbutamol.  Responses were classified using the American Thoracic Society (ATS)/European Respiratory Society (ERS) criteria and patients were classified as reversible and irreversible.

Result:  There was a clear positive correlation between FEV₁ reversibility and FVC reversibility. FEV₁ increased significantly with onchodilator in 25% of COPD patients, a response that was normally distributed.  FVC reversibility was seen in 62.5% of COPD

Conclusion:  COPD patients on the mild side of the severity spectrum differ from patients on the severe side regarding the association between their onchodilator flow and volume responses.

Article: Download PDF    DOI : https://www.doi.org/10.36106/paripex  

Cite This Article:

Dr. Ajithkumar. C. S., Bronchodilator reversibility in chronic obstructive pulmonary disease, PARIPEX‾INDIAN JOURNAL OF RESEARCH : Volume-7 | Issue-4 | April-2018

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