Autologous platelet rich plasma with microneedling in the treatment of atrophic facial acne scars: a pilot study

DR.SHARAD MEHTA; DR.VAISHALI MASATKAR

Volume : VIII, Issue : V, May - 2019

Autologous platelet rich plasma with microneedling in the treatment of atrophic facial acne scars: a pilot study

Dr. Sharad Mehta, Dr. Vaishali Masatkar

Abstract :

Background: A proposal has recently been made regarding the potential adjuvant use of platelet–rich plasma (PRP) with microneedling for the correction of acne scars. Aim and objective: To evaluate the efficacy and safety of autologous PRP combined with microneedling in the treatment of atrophic acne scars. Materials and methods: 30 patients were enrolled in the study. They were treated with intradermal autologous PRP followed by microneedling using 1.5mm diameter dermaroller and then topical application of PRP. Each patient underwent 4 sittings at an interval of 4 weeks. Photographic assessment was done at each visit and then after 3 months. Quantitative global acne scarring assessment tool based on the type and number of scars was used to assess the severity. The response to treatment was evaluated by objective and subjective methods. Results: On a four–point scale for quantitative assessment of clinical improvement of skin smoothness, out of 30 patients, 6 patients showed very good reduction. Majority of the patients (17/30, i.e. 56.67%) showed good reduction, 6 patients showed moderate and 1 patient showed minimal reduction. Rolling and superficial box scars showed higher significant improvement when compared with ice pick and deep box scars (p=0.0006). Patient's satisfaction of improvement was comparable with physician's observations. No serious adverse effects were noted during the study. Conclusion: Autologous platelet rich plasma with microneedling is both effective and safe treatment for atrophic acne scars in Indian skin