A STUDY OF SERUM VITAMIN D IN PSORIATIC PATIENTS IN A TERTIARY CARE HOSPITAL OF ASSAM.

DR. MALAVIKA BARMAN; DR. NIRMALI MATTACK

Volume : VIII, Issue : IX, September - 2019

A STUDY OF SERUM VITAMIN D IN PSORIATIC PATIENTS IN A TERTIARY CARE HOSPITAL OF ASSAM.

Dr. Malavika Barman, Dr. Nirmali Mattack

Abstract :

Psoriasis vulgaris (PV) is a common chronic autoimmune disease manifesting as thick scaly red plaques on the skin. The role of vitamin D is considered to vary, and some evidence suggests vitamin D to be a modulatory factor of the activity in dendritic cells and keratinocytes, or the proliferation in T–cells. Serum 25 hydroxycholecalciferol and serum calcium were estimated in 40 patients of psoriasis vulgaris and compared statistically with the values of 40 age and sex matched healthy controls. 25 hydroxycholecalciferol was estimated in both the case and the control group by chemiluminescence method in VITROS 5600. Calcium was estimated using reflectance photometry method in the same machine. The values obtained were statistically evaluated. The mean value of vitamin D was significantly lower in the case group than in the control group (p<0.01). No significant difference was found in the calcium levels between the two groups.