A Retrospective Cross Sectional Study on Pattern & Distribution of Pediatric Hematological Malignancies in Central part of India

Dr Bimla Banjare; Dr Amit Kumar Bhardwaj; Dr Riti Sharma

Volume : IX, Issue : VIII, August - 2020

A Retrospective Cross Sectional Study on Pattern & Distribution of Pediatric Hematological Malignancies in Central part of India

Dr Bimla Banjare, Dr Amit Kumar Bhardwaj, Dr Riti Sharma

Abstract :

Hematological Malignancies (HMs) consists of a diverse group of neoplastic diseases involving Bone Marrow, Lymph nodes or other Secondary Immune Organs. Conventionally, HMs represents 2 major group of diseases – Leukemia & Lymphoma. All Hematological Malignancies are on the rise as compared to few decades back worldwide but, it’s major unt is faced by the under developed countries of the world. A retrospective study in a Government Teaching Hospital was undertaken to characterize Pattern and Distribution of HMs in children in Chhattisgarh state of India. A total number of 65 Bone Marrow Aspiration Cytology cases were evaluated from 1st January 2019 to 31st December 2019 for a period of 1 year. Pediatric Population was categorized into 3 age groups – 0–2 years, 2–12 years and 12–16 years. Male to Female ratio was 2.4:1 in our study with most cases being of Acute Leukemias (95.4%). On further evaluation, ALL had highest numbers with 37 cases (57.0 %) followed by Acute Leukemia and AML with 14 (21.52%) & 10 (15.38%) cases respectively. The highest number of cases were seen in 2–12 years age group (n=49, 75.4%) implying that children of such age group presenting with signs and symptoms of HMs must be thoroughly evaluated for early diagnosis and treatment.