IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-8-26461 Original Research Paper GLYCOSYLATED HAEMOGLOBIN AND ITS CORRELATION WITH ULCER AREA IN DIABETIC FOOT ULCERS Shailendra Rai Dr. August 2020 9 8 01 02 ABSTRACT

Introduction– Diabetic foot ulcer is most frequent and distressing complication of type 2 diabetes mellitus (T2DM). Glycolysated hemoglobin represents the chronicity of disease and is used to monitor ulcer healing. We studied the correlation between glycosylated hemoglobin with ulcer area. Methodology– This is a descriptive study of 100 newly diagnosed T2DM with foot ulcers. Blood test for HbA1c has been performed. All the ulcers are washed and debrided. The ulcer parameters are measured, ulcer area is calculated and compared with HbA1c. Results– A total of 100 patients has been studied with male predominance. The mean age of presentation is 49.23 years (26– 87years). Fasting blood glucose is more than 110 mg/dl in all the patients. More than half of patients has HbA1c greater than 7%. Majority of patients has ulcer duration of less than 6 months. Ulcer area is less than 10cm2 in most of the cases followed by area of 10–20cm2 in 31 patients. Most of the patient has Hb1Ac greater than 7% and ulcer size of less than 10cm2. Among patients with ulcer larger than 20cm2, no significant difference is found in patients with HbA1c either <7% or >7%. Summary– Glycosylated hemoglobin is being used to study the chronicity of the disease. However, no correlation can be established between the ulcer area and glycosylated hemoglobin.