IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-8-26386 Original Research Paper Comparison of two different doses of dexmedetomidine as an adjuvant to caudal ropivacaine for post operative analgesia in paediatric infra-umbilical surgeries Vikas Sharma Dr. Dr Shikha Soni Dr. August 2020 9 8 01 02 ABSTRACT

Background and aims: This study was undertaken to evaluate the optimal dose of dexmedetomidine added to caudal ropivacaine for postoperative prolongation of analgesia without any major adverse effects inchildren. Material and Methods: This was a prospective randomized double blinded study involving 74 children aged between 2 to 10 years of either sex, of ASA grade I and II undergoing elective infraumbilical surgeries. Group 1 received dexmedetomidine 1µg/kg along with 0.25% ropivacaine 1ml/kg caudally; and Group 2 received dexmedetomidine 2µg/kg along with 0.25% ropivacaine 1ml/kg for caudal anesthesia. Results: The mean duration of analgesia was significantly longer (p value = <0.0001) in group 2 (932.40± 53.98 mins) than group 1 (666.21 ± 35.81 mins). The total number of doses of rescue analgesics required and pain scores (p value = <0.05) were also less in group 2. Conclusion: Dexmedetomidine 2µg/kg as caudal adjuvant to 0.25%ropivacaine 1ml/kg significantly prolongs analgesia in children without any adverse effects as compared to dexmedetomidine 1µg/kg along with 0.25% ropivacaine 1ml/kg.