IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-9-8-26335 Original Research Paper Malignant mixed germ cell tumor of ovary: a rare combination of choriocarcinoma and embryonal carcinoma Deepika Sharma Dr. Dr. Shobha Mohindroo Dr. August 2020 9 8 01 02 ABSTRACT

Malignant germ cell tumors are relatively uncommon tumors comprising less than 5% of all ovarian neoplasm. 95% of the germ cell tumors are benign cystic teratoma. Most common mixed germ cell tumors are dysgerminoma with yolk sac tumor. Here we report cytology and histopathology of a rare case of malignant mixed germ cell tumor comprised of a large component of choriocarcinoma along with a small component of embryonal carcinoma in a 40 years old female. She presented with pain abdomen and increased serum levels of human chorionic gonadotropin and lactate dehydrogenase. Alpha feto protein and CA–125 levels were normal. Both these germ cell tumors are extremely rare entities individually as well as in combination. She was treated with surgical resection followed by chemotherapy.