This prospective study included consecutive 100 cases of abnormal uterine bleeding satisfying inclusion criteria in single institute. Abnormal uterine bleeding is most common complaint in gynecological and family practice with diverse etiology and presentation. Thyroid dysfunction was found to be much more prevalent in patients with abnormal uterine bleeding. Predominant thyroid dysfunction was hypothyroidism. Both hypothyroidism and hyperthyroidism were associated with large number of menstrual aberrations. Thyroid dysfunction should be considered as an important etiological factor for menstrual abnormality.