AIM: .Retinopathy Of Prematurity (ROP) is a retinal disorder seen in low birth weight and premature infants. It can be mild with no visual defects, or it may become aggressive with new vessels formation and progress to retinal detachment and blindness. Timely screening and treatment of ROP can prevent blindness. A screening program is needed for early diagnosis and secondary prevention of visual loss due to ROP in at–risk neonates. MATERIAL METHOD : Retinopathy of prematurity screening programme started in a newborn care unit of a tertiary care eye hospital according to guidelines of Rashtriya bal swasthya karyakram; Ministry of Health & Family Welfare– Government of India2017 .Babies born before 36 weeks or birth weight < 2000 gm receive first screening at 4 weeks of birth and small infants with period of gestation less than 28 weeks or less than 1200 grams birth weight screened early at age of 2–3 weeks after delivery. These babies were followed up till retinal vascularization completes. RESULT: Over a period of 6 months from September 2017 to March 2018 total of 321 preterm babies were screened for ROP. The incidence of ROP in 321 infants screened was 56 (17.44%). Stage1detected in 47 eyes, stage 2 in three eyes, and stage 3 in two eyes. Plus disease was seen in 4 eyes (1.2 %). CONCLUSION: Improved antenatal and postnatal care has given chances of survival to many premature babies, now their future sight is a combined responsibility of neonatologist, parents and ophthalmologist. Increasing burden require that all future and practicing ophthalmologist should participate in ROP screening programme.