Introduction: Intraoperative imprint cytology thyroid is reliable and cost effective method, provides excellent cellular details. The simplicity, speed and cost effectiveness along with its ability to maximize cell recovery from very small tissue piece makes Touch Imprint Cytology a valuable resource for experimental and diagnostic medicine. Aims & Objectives: To correlate between imprint cytology & histopathology of thyroid lesions. Materials & Methods: Intraoperative imprint cytology/scrape preparation of thyroid swelling taken, properly processed, interpreted and course of surgery was done accordingly. Later correlate with histopathology. Results & Analysis: Results of our study: sensitivity 95.2%, specificity 86.2%, positive predictive value 83.3%, negative predictive value 96.15% and accuracy rate of 90%. Conclusion: Intra operational diagnosis by imprint/ scrape preparation was rapid as well as cost benefit, can be performed in a tertiary care center where frozen section facility is not available. Thyroid malignancies successfully commented by imprint cytology and scrape preparation. Advantages: rapid intra operational diagnosis of lesion (benign/ malignant) avoid re excisional hazard, better cosmesis, excellent therapeutic action and decreased morbidity. The procedure is safe, rapid, easy, cost effective and very useful procedure in diagnosis of wide spectrum of thyroid diseases.