Introduction: Stroke is common emergency & common cause of physical disability. Relation between stroke & atherosclerosis is well known. Dyslipidaemia being precursor for atherosclerosis should be treated aggressively to reduce incidence of stroke and to improve the clinical outcome in the patients with stroke. Objectives: To study fasting serum lipid profile in patient with non–diabetic stroke and to determine significant correlation between them. To assess the role of aggressive control of dyslipidaemia on recovery of stroke. Material & Methods: Patients taken for the study subjected to Fasting lipid profile at presentation and follow – up at 12 weeks to re–check the fasting lipid profile and correlate recovery of stroke. Results: STC was abnormal in 22 patients at onset and 16 patients after 3 months of therapy. TG was abnormal in 68 patients at onset & 70 patients after 3 months of therapy. LDL was abnormal in 64 patients at onset & 40 patients after 3 months of therapy. HDL was abnormal in 76 patients at onset & 70 patients after 3 months of therapy. VLDL was abnormal in 68 patients at onset & 70 patients after 3 months of therapy. Correlation between mNIHSS score and lipid profile showed significant clinical improvement with reduction in LDL levels & corresponding P value is 0.000 which is highly significant. Correlation between MRS score and lipid profile showed a good clinical outcome with reduction in LDL levels & corresponding P value is 0.026 which is significant. Conclusion: Study showed higher levels of STC, TG, LDL, HDL, VLDL is not a risk factor for occurrence of ischaemic cerebro–vascular disease (CVD). Decrease in LDL levels shows significant improvement in clinical outcome.