Infection of the urinary tract is amongst one of the most common infections in the hospital as well as in the community. Causative agents may vary in patients depending on their age, gender and geographical location. Clinical symptoms may include burning sensation during urination, pain above pubic bone, fever, urgency and frequency of urination etc. Antimicrobial resistance is the major problem in the treatment for UTI throughout the world. Resistance could be due to indiscriminate use of antimicrobials, inappropriate dosing and short course of therapy with antibiotics. Availability of over the counter drugs all over the country has played an important role for this widespread resistance in antibiotics. In this article an attempt has been made to review the antibiotic resistance pattern in the commonly involved organisms causing urinary tract infections