Background: Ethics are the basic concept and fundamental principles of nurses conduct regarding the health care system. The knowledge of legal responsibilities is integral with the expanding clinical role and logical application of the planned, systematic and focused care, which should be the goal of Modern Nursing. Objective: To assess the knowledge and attitude of staff nurses regarding health care laws and ethics. Method: The research approach adopted for the study was Quantitative Research Approach. The research design adopted for the study was Descriptive Survey Design. Total 215 staff nurses were selected by using total enumerative sampling technique from MMIMS& R Hospital. The tools developed and used for data collection were structured knowledge questionnaire and five point Likert attitude scale, tools were prepared by focusing on knowledge and attitude respectively. Results: The study revealed that the mean of knowledge score of the staff nurses regarding health care laws and ethics was (7.07) with standard deviation (2.83) and mean of attitude score was (79.91) with standard deviation (8.03) respectively. The study concluded that staff nurses have average level of knowledge and had favorable attitude towards health care laws and ethics. There is moderately positive correlation between knowledge and attitude of staff nurses regarding health care laws and ethics.