Study was aimed to estimate of confidence level among student nurses in the performance of BLS. Objectives: To estimate the confidence level of B.Sc nursing final year students in the performance of BLS.To determine the association of Confidence level with selected student’s variables in the performance of BLS. Material and method: The study was a descriptive study conducted in different nursing colleges of Guwahati, Assam. Data was collected from 162 student nurses by using consecutive sampling technique. Self administered structured questionnaire on assessment of confidence level was used.The collected data was analyzed using SPSS version 20.Finding:The study showed that 19% of participant were not confident; 62% of participant were confident;19% of participant were highly confident. The mean score of not confident among participant was 16.54; mean score of confident was 21.90 and mean score of highly confident was 27.06. The study finding also revealed that there was significant association of Confidence level with selected student’s variables namely Participation in training program/ workshop on BLS (df=2,p=0.021), Observation of BLS procedure on patient (df=2,p=0.012) at 0.05 level of significance. Conclusion: The results indicated that all nursing students need to improve their confidence level in performing BLS. It is crucial for nursing students to participate in CPR courses in order to refresh and update their theoretical knowledge and performance skills which will contribute to improve the safety and effectiveness of care.