Background: – Dengue fever is an infectious disease which is difficult to distinguish from other prevalent viruses as there are no specific markers that can diagnose the disease early. Because it is a disease that can evolve with serious consequences and even be fatal, this study aimed at analyzing laboratory dynamics in order to try to identify biomarkers that are predictive of severity. Aim & Objectives:–To study the impact of hematocrit values and Platelet count values on clinical outcome of dengue fever and to compare hematocrit and Platelet counts as predictive factors for complications in dengue fever. Methods: – A total of 2314 clinically and serologically proven dengue cases were analyzed over 1 year from January to December 2017, along with hematocrit and relevant hematology data (obtained from patients clinical case records). Conclusion:– Raise in Haematocrit in dengue was associated with dengue associated complications like ARDS , Circulatory shock and Death. It also showed that the incidence of hospitalization to critical care unit is statistically significant in patients with raised haematocrit. On the contrary, Thrombocytopenia in dengue did not show any statistically significant association while predictiong morbidity and mortality in dengue patients