Volume : II, Issue : IX, September - 2013

Synthesis and Characterization of Some New Substituted Pyrimidine Derivatives

S. Rajalakshmi, S. Aruna

Abstract :

Pyrimidindiones are associated with the oad spectrum of biological activities including antimicrobial, anticancer, anti–inflammatory, etc. These findings prompted us to synthesize compounds containing pyrimidine moiety and to evaluate for anti–inflammatory activity. A series of new substituted pyrimidine derivatives have been synthesized by condensing substituted phenyl cyano ester with urea and thiourea. All these pyrimidine derivatives are characterized by IR, 1H, 13C NMR and Mass spectral studies. These compounds are found to possess anti–bacterial activity

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

S. Rajalakshmi, S. Aruna Synthesis and Characterization of Some New Substituted Pyrimidine Derivatives International Journal of Scientific Research, Vol : 2, Issue : 9 September 2013

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