Study of Prevalence of Weak D Antigen (Du) Amongst Supposed Rh Negative Blood Donors in a Tertiary Care Hospital of Jharkhand

Dr. Ramesh Kumar Srivastava; Dr. Niraj Prasad; Dr. Doyel Halder

Volume : VII, Issue : VIII, August - 2018

Study of Prevalence of Weak D Antigen (Du) Amongst Supposed Rh Negative Blood Donors in a Tertiary Care Hospital of Jharkhand

Dr. Ramesh Kumar Srivastava, Dr. Niraj Prasad, Dr. Doyel Halder

Abstract :

The major antigen of Rh blood group system is the Rh D antigen.. The �weak D� actually refers to red cells with the aberrant Rh–D protein expressing reduced memane surface D antigen.This study was conducted in the Blood Bank of Rajendra Institute of Medical Sciences, Ranchi, Jharkhand. It is a retrospective study and data of 3yrs from January, 2015 to December, 2017 was collected.A total of 1,66,000 healthy blood donors were tested out of which total of 2013 (1.21%) blood donors turned out to be Rh–D negative during a span of 36 months from January, 2015 to December, 2017 and on further testing 7 (0.35%) of them turned out to be weak D positive.For safe blood transfusion & to prevent transfusion related complications, comprehensive national transfusion guidelines need to be laid down to standardize the protocol for D antigen testing for donors as well as patients.