Volume : VIII, Issue : V, May - 2019
Study of Histopathological Spectrum of Ovarian Lesions and Neoplasms
Gomathi Srinivasan, Saravanan. B, Rajavelu Indira, Madhumitha
Abstract :
The most common lesions encountered in the ovary are functional or benign cysts and tumours. Neoplastic disorders can be grouped according to their origin from each of the three main ovarian cell types (1)Mullerian epithelium (2)Germ cells (3)sex cord –stromal 〖cells.〗^1 About 80% of ovarian tumours are benign and these occur mostly in young women between the ages of 20 and 45 years. Borderline tumours occur at slightly older age group. Malignant tumours are more common in older women between the ages of 45 and 65 〖years〗^1. Ovarian cancer accounts for 3% of all cancers in females and is the fifth most common cause of death due to cancer in women 1 The classification of ovarian neoplasms as per WHO classification is oadly grouped into following categories1 Surface epithelial–stromal tumours Sex cord –stromal tumours Germ cell tumours Metastatic cancer from non–ovarian primary The most common symptoms of ovarian tumours are abdominal pain and distension, urinary and gastrointestinal tract symptoms due to compression by tumour or cancer invasion and vaginal bleeding. Benign forms may be entirely asymptomatic. METHODS; All clinical details and data from case sheet and patient history are collected and analysed for all the patients who underwent surgery for ovarian pathology / neoplasms in the Department of Obstetrics and Gynaecology, Govt. Omandurar Medical College and Institute of social obstetrics and Govt. Kasturba Gandhi Hospital Chennai, from Jan 2017 to Dec 2017. The Study period of this study was from Jan 2017 to Dec 2017. Multiple sections were taken from the neoplasms and tissues were processed in Automated tissue processor and Paraffin blocks made. Statistical analysis of the data was analysed. RESULTS; Total number of specimens received were 50. The Histopathology types seen in the study group were Among the neoplastic lesions of the ovary, Benign neoplasms formed the majority of neoplasms. Among the Benign neoplasms, Benign Serous cystadenoma formed the majority with 19 cases, followed by serous cystadenofioma and Benign cystic teratoma with 8 cases each and Mucinous cystadenoma with 7 cases. The predominant age group affected was 41 to 50 years with 17 cases followed by 31 to 40 years with 10 cases, with the predominant neoplasm being Benign surface epithelial tumour, with the majority of cases being Benign serous cystadenoma. CONCLUSION; Ovarian tumours are the common forms of neoplasia in women. Ovarian neoplasms account for a disproportionate number of fatal cancers, being responsible for almost half of the deaths from cancer of female genital tract because many of these ovarian neoplasms cannot be detected early in their development. Hence there is a need for histopathological diagnosis for these tumours, which cannot be diagnosed and categorised merely by clinical and radiological background. Therefore, specific histopathological diagnosis is necessary as it may aid in the further management of cases, through which cancer deaths can be prevented by utilizing better treatment modalities
Keywords :
Cystadenoma Cystadenofibroma Cystadenocarcinoma Benign Cystic Teratoma Benign Fibrothecoma Krukenberg Tumour Borderline Serous Borderline Mucinous Neoplasm.
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DOI : 10.36106/ijsr
Cite This Article:
STUDY OF HISTOPATHOLOGICAL SPECTRUM OF OVARIAN LESIONS AND NEOPLASMS, Gomathi Srinivasan, Saravanan.B, Rajavelu Indira, Madhumitha INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-5 | May-2019
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STUDY OF HISTOPATHOLOGICAL SPECTRUM OF OVARIAN LESIONS AND NEOPLASMS, Gomathi Srinivasan, Saravanan.B, Rajavelu Indira, Madhumitha INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-5 | May-2019
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