SPECTRUM OF PATHOGENIC BACTERIA ISOLATED FROM THE ENDOTRACHEAL TUBE ASPIRATES AND THEIR ANTIBIOTIC SENSITIVITY PATTERN IN A TERTIARY CARE CENTRE RANCHI

Archana; Manoj Kumar; A.K.Sharma

Volume : IX, Issue : VIII, August - 2020

SPECTRUM OF PATHOGENIC BACTERIA ISOLATED FROM THE ENDOTRACHEAL TUBE ASPIRATES AND THEIR ANTIBIOTIC SENSITIVITY PATTERN IN A TERTIARY CARE CENTRE RANCHI

Archana, Manoj Kumar, A. K. Sharma

Abstract :

Background: Pneumonia is the inflammation of the lung tissue caused by infection of bacteria, virus, fungi. Several bacterial etiological agents are known to cause the infection, studies have shown several gram negative bacteria like Pseudomonas spp, Klebsiella spp, Proteus, Acinetobacter spp and gram positive bacteria such as Streptococcus, Staphylococcus spp are known to cause infection. In the present study we aim to evaluate the spectrum of bacterial isolates and their antibiotic sensitivity pattern isolated from Endo tracheal tube aspirates (ETA). Materials and Methods: The retrospective study was carried out in a tertiary care centre over a period of fifteen months of total 858 ETA samples. The isolates were evaluated and identified with antibiotic sensitivity pattern. Results: The overall ETA specimen processed in 15 months were 858, in which culture positive were 582 cases (69%). The organisms isolated were Klebsiella pneumoniae grown in 309 samples (53%), Pseudomonas aeruginosa grown in 157 samples (27%), Acinetobacter spp grown in 35 samples (5.8% ), Escherichia coli grown in 30 samples (5.2%), Proteus spp grown in 11 samples (2%) and gram positive cocci grown in 40 samples (7%).In total gram positive cocci isolated, Methicillin resistant Staphylococcus aureus were grown in 27 samples. Most of Klebsiella pneumoniae isolates came sensitive to Colistin and most of Pseudomonas aeruginosa came sensitive to colistin, Meropenem, Imipenem. Conclusion: The present study has shown the most common isolate at our tertiary centre was Klebsiella spp. followed by Pseudomonas aeruginosa, Acinetobacter spp, Escherichia coli and Proteus. In gram positive bacteria the common organism isolated was Staphylococcus aureus. Our results contribute to, evaluate the common prevalent organisms causing pneumonia and also helps in improving the epidemiological knowledge.