Serum Tissue Non Specific Alkaline Phosphatase Isoenzyme Level in Chronic Periodontitis Patients

Dr. Gopu Chandran Lenin Perumal; Prof. Dr. Senthil Kumar; Prof. Dr. Mythili .R; Dr. Subashini Suyambukesan

Volume : III, Issue : IX, September - 2014

Serum Tissue Non Specific Alkaline Phosphatase Isoenzyme Level in Chronic Periodontitis Patients

Dr. Gopu Chandran Lenin Perumal, Prof. Dr. Senthil Kumar, Prof. Dr. Mythili . R, Dr. Subashini Suyambukesan

Abstract :

Purpose: The purpose of this study was to estimate and compare the levels of tissue non–specific alkaline phosphatase isoenzyme in serum of healthy individual and in chronic periodontitis patients. Materials and Methods: Serum samples were obtained from 20 individuals. 10 from healthy individuals and 10 from chronic periodontitis patients. The samples were used to determine the tissue non – specific alkaline phosphatase isoenzyme (TNSALP) level.Results:Evaluation and comparison of the tissue non – specific alkaline phosphatase isoenzymeactivity between the control and chronic periodontitis patient group showed a decrease in tissue non – specific alkaline phosphatase levelamong chronic periodontitis patients. Conclusion: The measurement of tissue non – specific alkaline phosphatase level in serum can be considered as an enzymatic assay for evaluating the severity and progression of chronic periodontitis. This might provide useful information if monitored successively over a period of time.