Volume : III, Issue : IX, September - 2014

Serum Lipids and Lipoprotein (a) Levels in Psoriasis

Dr K. P. Latha, Dr Anil Kumar . A. S

Abstract :

Psoriasis is a chronic inflammatory skin disease associated with an increased cardiovascular risk profile with multiple underlying factors. Psoriasis has been associated with abnormal plasma lipid metabolism and oxidative stress. Lipoprotein (a) [Lp(a)] has been implied in cardiovascular disease and has been reported to be elevated in patients with psoriasis. The present study was to determine the serum lipid disturbances and to assess the significance of Lipoprotein (a) levels in subjects with psoriasis. 30 patients with psoriasis in the age group of 15 to 75 years were studied and compared with 30 healthy controls matched in terms of age, gender and body mass index. Serum TC, TG, VLDL–C, TC/HDL–C ratio levels were significantly higher in the psoriasis patients compared to controls. LDL–C was higher and HDL–C was lower respectively in the cases compared to controls, with the difference which was statistically insignificant. Patients with psoriasis showed significantly higher serum levels of Lp(a) compared to controls. Thus Patients with Psoriasis could be considered as a high risk group for atherosclerosis and cardiovascular diseases because of susceptibility in lipid profile, Lipoprotein content and increased oxidant stress.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr K.P. Latha, Dr Anil Kumar .A.S Serum Lipids and Lipoprotein (A) Levels in Psoriasis International Journal of Scientific Research, Vol : 3, Issue : 9 September 2014

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