Volume : V, Issue : VI, June - 2016

SERO PREVALENCE OF DENGUE NS1 ANTIGEN IN S.P.MEDICAL.COLLEGE, BIKANER (RAJ)

Dr. Rohitash K, Dr. Anita Sharma, Dr. Ajayb. R

Abstract :

 Introduction: Dengue is one of the most serious mosquito–borne viral infections affecting tropical and subtropical countries in the world. Since there is no immune prophylactic or specific antiviral therapy available, timely and rapid diagnosis plays a vital role in patient management and implementation of control measures. The present study was planned to diagnose the dengue infection by detecting dengue NS–1 antigen & to study the seroprevalence of dengue NS–1 antigen Material and Methods: Dengue NS–1 testing by immunochromatography was performed during sept and the data were analyzed retrospectively. A total 928 serum samples sent from Department of Medicine, Sardar Patel Medical College, Bikaner for the detection of Dengue NS–1Ag. Results: Total samples tested were 928 out of which NS–1 seropositive were 174 (18.75%). All positive were confirmed by NS 1 ELISA test. Male:female ratio was 2:1 .More nos of cases were seen in age group 20– 30 years that is 92 (52.87%) .Urban:Rural ratio was 4:1 . Fever was the commonest presentation in all suspected patients 928 (100%) associated with headache in 898, associated with muscle pain in 814 then fever with headache with muscle pain in 847. Fever with rash in 32, fever with retroorbital pain in 8 and fever with haemorrhagic manifestation in 7 patients were observed. Patients with platelet count less than 50,000 were 39 (22.41%), 50,000 to < 1,00,000 were 58 (33.33%) and > 1,00,000 were 77(44.25%). According to day of fever, highest nos of seropatients pts were seen in 4th day that is 112 (64.36%) that followed by 3rd day that is 35 (20.11%) and from that more nos of seropositive male 68 (39.08%) and seropositive female 47(27.01%) were seen in 4th day of fever that is followed by on 3rd day 20 (11.49%) seropositive male and 4 (2.29%) seropositive female. Conclusion: New dengue virus strains and serotypes will likely continue to be introduced into urban areas where the densities of Aedes aegypti are at high levels. So, for the early and rapid diagnosis NS 1 immunochromatography are very helpful in dengue infection.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

DR. ROHITASH K, DR. ANITA SHARMA, DR. AJAYB.R SERO PREVALENCE OF DENGUE NS1 ANTIGEN IN S.P.MEDICAL.COLLEGE, BIKANER (RAJ) International Journal of Scientific Research, Vol.5, Issue : 6 JUNE 2016

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