Role of Allergic mucin in Allergic Fungal Rhinosinusitis

Dr. TanviAnoop Lohiya; Kshitij Dhaval Shah; Dr. Renuka Anil Bradoo

Volume : IV, Issue : VII, July - 2015

Role of Allergic mucin in Allergic Fungal Rhinosinusitis

Dr. Tanvianoop Lohiya, Kshitij Dhaval Shah, Dr. Renuka Anil Bradoo,

Abstract :

AFRS is a non–invasive form of fungal rhinosinusitis which develops as a Type I hypersensitivity to fungus. Patients commonly present with chronic rhinosinusitis with nasal polyps, inhalant atopy, elevated total serum immunoglobulin E (IgE), and sinus–obstructing inspissates of a characteristic extramucosal �peanut buttery� eosinophil–rich material called �allergic mucin� that contains sparse numbers of fungal hyphae and CT findings of �double densities� The treatment is surgery, complemented by medical therapy in the form of systemic steroids or antifungals such as Itraconazole. This study has been undertaken to assess the significance of allergic mucin in AFRS. The study concludes that allergic mucin has a strong positive correlation and hence is a major diagnostic criteria for AFRS.