“Rhabdomyolysis”; Elevated CPK values following  Seizures

Dr. VibhutiMaru; Dr. SmritiDewan; Dr. Reeta Dhar

Volume : IV, Issue : IX, September - 2015

“Rhabdomyolysis”; Elevated CPK values following Seizures

Dr. Vibhutimaru, Dr. Smritidewan, Dr. Reeta Dhar

Abstract :

<p>Male aged 40 years was admitted with H/o fall , seizures&amp; fever. Patients blood sample was received in the laboratory for investigations. Pts total leukocytic count was more than normal and CPK values were extremely high (51000 U/L). The patient had elevated serum Creatinine, Blood Urea Nitrogen (BUN) Serum Uric acid, Serum Sodium, Serum Phosphorous, Bilirubin, SGOT, SGPT , deranged prothrombin time and decreased potassium, calcium, protein and serum albumin. Also the urine colour and dipstix test suggested presence of myoglobin in urine. Retrospectively the clinical details of the patient mentioned that he had history of fall with three episodes of generalized tonic clonic convulsions. Also, the patient was hypertensive and a known case of chronic liver disease secondary to alcoholism and had no history of cardiac or renal disease. The above investigations along with the clinical details suggested that the patient might be a case of Rhabdomyolysis leading to acute renal failure with extremely high CPK values. In spite of repeated haemodialysis and electrolytes management, the patient could not recover and succumbed to death on third day of admission.In case of very high levels of CPK values in patients of Rhabdomyolysis leading to acute Renal Failure, a conclusive diagnosis should be made at the earliest.</p>