PATHOPHYSIOLOGICAL STUDY OF MENINGIOMA WITH SPECIAL REFERENCE ON VARIANTS AND GRADING IN RIMS RAIPUR

Dr Chandrahas kant Choudhary; Dr C.M. Verma; Dr Brajendra kumar

Volume : VI, Issue : IV, April - 2017

PATHOPHYSIOLOGICAL STUDY OF MENINGIOMA WITH SPECIAL REFERENCE ON VARIANTS AND GRADING IN RIMS RAIPUR

Dr Chandrahas Kant Choudhary, Dr C. M. Verma, Dr Brajendra Kumar

Abstract :

Meningioma are histologically diverse group of tumors derived from meningothelial cells. In our study incidence, clinical features, anatomical location, histopathological spectrum of Meningioma were studied in RIMS RAIPUR. The study included 500 CNS tumors operated over five years duration. All the cases of meningioma were studied by histopathological examination using H and E staining. Immunohistochemistry was done as and when required. In our study, meningiomas accounted for 17.6 % (88 cases) of the CNS tumors. The most common age group was 40–59 years (59%). Female predominance (69.31%) was noted . Intracranial meningiomas (90.90%) were common than spinal meningiomas. The most common histopathological type was meningotheliomatous meningioma (50%). 94.3% of the meningioma was WHO grade I tumor. Brain invasion and mitosis were statistically significant histological features for determining Meningioma Grade.Meningiomas display a wide diversity of histopathological appearances. Majority are benign.