Volume : VIII, Issue : II, February - 2019
Novel non-invasive diagnostic procedure for birth asphyxia related renal injury in term newborns
Dr. Karan Joshi, Dr. Darshan Kataria
Abstract :
Introduction– Perinatal asphyxia is a condition defined as hypoxemia, hypercapnea and acidosis in neonate.
Aims & objectives– To evaluate the utility of urinary uric acid levels within 48 hours of birth as means of identifying kidney injury in term asphyxiated neonates.
Material and methods–
Study design– Prospective observational cohort study
Settings– Tertiary level hospital in central India
Duration– July 2017 to June 2018.
Participants– Due to financial constraints 100 neonates were enrolled.
Statistical analysis was performed by IBM SPSS version 22 and Microsoft Excel. Test of significance by Mann–Whitney U test.
Results– The mean rank of urine uric acid level (24.13 vs. 15.46) was significantly higher in term asphyxiated as per urine output (p=0.031).
Conclusions– Urine uric acid value of 22.3 micromole/24 hr has a sensitivity (66.7 %), specificity (91.4%) for detecting kidney injury in asphyxiated term newborns.
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DOI : 10.36106/ijsr
Cite This Article:
NOVEL NON-INVASIVE DIAGNOSTIC PROCEDURE FOR BIRTH ASPHYXIA RELATED RENAL INJURY IN TERM NEWBORNS, Dr. Karan Joshi, Dr. Darshan kataria INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-2 | February-2019
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NOVEL NON-INVASIVE DIAGNOSTIC PROCEDURE FOR BIRTH ASPHYXIA RELATED RENAL INJURY IN TERM NEWBORNS, Dr. Karan Joshi, Dr. Darshan kataria INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-2 | February-2019
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