Evaluation of antioxidant activity of  Artocarpus hirsutus methanolic fruit  extract: An in vitro study

Vinay suvarna M N; Ramesh B S; Venkatachalapathy R; Makari Hanumantappa K; Ramaganesh C  K; Karunakar B S

Volume : II, Issue : XII, December - 2013

Evaluation of antioxidant activity of Artocarpus hirsutus methanolic fruit extract: An in vitro study

Vinay Suvarna M N, Ramesh B S, Venkatachalapathy R, Makari Hanumantappa K, Ramaganesh C K, Karunakar B S

Abstract :

Antioxidants are substances that can scavenge free radicals, thereby protecting the body against their potentially damaging effects. Research suggests that there is increased oxidative stress in combination with reduced antioxidant status; this results in greater vulnerability to the damaging effects of free radicals. High levels of reactive oxygen species (ROS) can initiate impaired functioning and destruction of neurons and other bodily cells. Many plants and herbs have potent antioxidant activity, Artocarpus hirsutus show potency of antioxidant activity, but the effects of these have not been studied previously. The methanolic fruit extract of Artocarpus hirsutus was found to be effective in DPPH radical scavenging activity. The DPPH radical scavenging activity of the extract was increased with the increased concentration of crude plant methanolic fruit extract. The reducing power of the extract was carried out with ascorbic acid as a standard reducing agent. The methanolic fruit extract was potentially exhibited concentration dependent DPPH radical scavenging and reducing power is an increased quest to obtain natural antioxidants with oad-spectrum actions. The majority of the rich diversity of Indian medicinal plants is yet to be scientifically evaluated for such properties. In present work an attempt has been carried out to evaluate antioxidants of Artocarpus hirsutus widely found in Western Ghats regions.