Volume : VIII, Issue : III, March - 2019
Effects of Letrozole on Patients with Uterine Fibroids At Tertiary Care Hospital in Western Rajasthan
Kamlesh Yadav, Jyoti Meghwal
Abstract :
Background– Letrozole, the aromatase inhibitor has been reported to decrease the size of symptomatic fioid & uterine volume with improvement in the haemoglobin levels and pain. Method–100 cases, from department of Gynae. & Obst. , PBM Hospital , SPMC ,Bikaner were included in this study from 1st Aug. 2017 to 31th July. 2018. After complete general & Gynaecological evaluation, all 100 cases were prescribe to take tab. Letrozole 5mg/day continuously for 3 months & effects of the drugs were observed. Result–Average reduction of fioid volume by 23.65 % and uterine volume by 69.45% was seen. Haemoglobin concentration increased from 8.4 g/dl to 10.4g/dl and overall improvement in symptomatology score was observed. Joint pain, hot flushes , sweating, hair loss & hyper pigmentation were the main adverse effects observed and were self limiting . Conclusion– Letrozole the aromatase inhibitor may represent a new generation of medication for the treatment of uterine fioid and associated symptoms. Larger clinical trials are needed, however, to fully evaluate their safety and efficacy.
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DOI : 10.36106/ijsr
Cite This Article:
EFFECTS OF LETROZOLE ON PATIENTS WITH UTERINE FIBROIDS AT TERTIARY CARE HOSPITAL IN WESTERN RAJASTHAN, Kamlesh Yadav, Jyoti Meghwal INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-3 | March-2019
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EFFECTS OF LETROZOLE ON PATIENTS WITH UTERINE FIBROIDS AT TERTIARY CARE HOSPITAL IN WESTERN RAJASTHAN, Kamlesh Yadav, Jyoti Meghwal INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-3 | March-2019
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