Volume : VI, Issue : IX, September - 2017
EFFECT OF DEXMEDETOMIDINE ON EMERGENCE FORM NEUROANAESTHESIA IN PATIENTS UNDERGOING SUPRATENTORIAL CRANIOTOMY
Dr. Dilip Kumar Kulkarni, Dr. Anshul Yadav, Dr. R. Goipnath
Abstract :
Background: The dexmedetomidine is a highly selective α–2 adrenoreceptor agonist and frequently used as an adjuvant to anesthesia for perioperative hemodynamic stability. We have contemplated to study haemodynamic stability and the emergence response at the time of extubating in patients undergoing supratentorial tumour surgery.
Methods: Fifty ASA grades I/II patients, aged 14–65 years scheduled for elective surgery were divided randomly into two equal groups (n=25). In the study group dexmedetomidine was infused at the rate of 0.5 µg/kg/hr and control group received normal saline during the study period. The study period was from the start of dural closure to the closure of skin incision. The hemodynamic changes, emergence characteristics and complications during the study period were recorded.
Results: Heart rate and mean arterial pressure were significantly lower in dexmedetomidin group as compared to control group (p<0.05) at the time extubation and up to 10 minutes after extubation. Blunting of tachycardia response and the hypertensive response to extubation were observed in these patients. Statistically significant (p< 0.05) difference is found in emergence agitation, bucking, coughing and shivering in between the two groups. The time to eye opening and time for extubation were less in study group compared to control group but not statistically significant.
Conclusions: Dexmedetomidine attenuates stress responses to various noxious stimuli at the time of extubation, maintains haemodynamic stability, and blunts tachycardia and hypertensive response. At the same time it also reduces the emergence reactions to extutbation in patients undergoing supratentorial craniotomy
< clear="all" style="page–eak–before:auto;mso–eak–type:section–eak" />
< clear="all" style="page–eak–before:always;mso–eak–type:section–eak" />
Keywords :
Article:
Download PDF
DOI : 10.36106/ijsr
Cite This Article:
Dr.Dilip Kumar Kulkarni, Dr.Anshul Yadav, Dr.R.Goipnath, EFFECT OF DEXMEDETOMIDINE ON EMERGENCE FORM NEUROANAESTHESIA IN PATIENTS UNDERGOING SUPRATENTORIAL CRANIOTOMY, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-6 | Issue-9 | September-2017
Number of Downloads : 291
References :
Dr.Dilip Kumar Kulkarni, Dr.Anshul Yadav, Dr.R.Goipnath, EFFECT OF DEXMEDETOMIDINE ON EMERGENCE FORM NEUROANAESTHESIA IN PATIENTS UNDERGOING SUPRATENTORIAL CRANIOTOMY, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-6 | Issue-9 | September-2017
Our Other Journals...
-
Indian Journal of
Applied Research Visit Website -
PARIPEX Indian Journal
of Research Visit Website -
Global Journal for
Research Analysis Visit Website