Volume : VII, Issue : II, February - 2018
Effect of Blood 25–hydroxy vitamin D [25(OH)] levels on Prediabetes patients : A Meta–analysis of Randomised Control Trials
Rekha Choudhary, Prashant Hisalkar, Poorvi Gupta
Abstract :
Background: Emerging evidence suggests that vitamin D may play a role in the development of diabetes. This meta–analysis was done to evaluate effect of Vitamin D on blood glucose level among pre–diabetes patients. Objective: To evaluate the effect of vitamin D on glycaemic control in Prediabetes in different RCT performed. Methods: A literature search was conducted of MEDLINE, the Cochrane Liary, (CINAHL), Scopus, Web of Science through the reference lists of relevant articles until end of November 2017. Studies were included if they were RCT of vitamin D or vitamin D analogues in pre–diabetes. Treatment effect was estimated according to mean difference in the changes 2–h oral glucose tolerance test plasma glucose, fasting plasma glucose and HbA1C between vitamin D and control groups. Results: A total of 10 randomized controlled trials were included. Vitamin D did not significantly improve 2–h oral glucose tolerance test plasma glucose: the mean differences were – 0.06 (95% CI –0.36 to 0.24) and –0.23 mmol/l (95% CI –0.65 to 0.19), respectively. Conclusions: Low beneficial effect of Vitamin D improving the blood glucose levels in prediabetes was identified.
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DOI : 10.36106/ijsr
Cite This Article:
Rekha Choudhary, Prashant Hisalkar, Poorvi Gupta, Effect of Blood 25-hydroxy vitamin D [25(OH)] levels on Prediabetes patients : A Meta-analysis of Randomised Control Trials, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH :
Volume-7 | Issue-2 | February-2018
Number of Downloads : 210
References :
Rekha Choudhary, Prashant Hisalkar, Poorvi Gupta, Effect of Blood 25-hydroxy vitamin D [25(OH)] levels on Prediabetes patients : A Meta-analysis of Randomised Control Trials, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-2 | February-2018
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