Drug Rash, Eosinophilia and Systemic Symptoms Syndrome of ATT induced â€“ A Rare Case Report.

V.Chandra Sekhar; Madhusudan R. Jaju; Shashank Kumar Srivastav

Volume : V, Issue : X, October - 2016

Drug Rash, Eosinophilia and Systemic Symptoms Syndrome of ATT induced â€“ A Rare Case Report.

V. Chandra Sekhar, Madhusudan R. Jaju, Shashank Kumar Srivastav

Abstract :

DRESS syndrome (Drug Rash, Eosinophilia and Systemic Symptoms) is a potentially life–threatening syndrome including severe eruption, fever, hypereosinophilia and internal organ involvement. We report a case of this syndrome in a 40–year old female with pulmonary Koch�s, Lt pleural biopsy–Granulomata with small necrotic foci and was started on ATT, on which she developed skin rash, eosinophilia, liver injury after about six weeks of ATT which lead us to finding of DRESS Syndrome–ATT induced (ethambutol/rifampicin). This case resolved with ATT withdrawal. Rapid diagnosis is crucial as prompt withdrawal of offending drug is the key to treatment, while the potential role of corticosteroids remains controversial.