Volume : III, Issue : XI, November - 2014

Diagnostic Value of Pleural Fluid Examination

Dr. Varsha Khant, Dr. R. N. Gonsai

Abstract :

Introduction:Both malignant and non malignant causes of effusion can be identified by relatively non invasive technique of pleural fluid cytology and cell count. Cytological study of the fluid is important because the cell population present is representative of a much larger surface Are than obtained by needle biopsy.Aims and Objective:  To identify various causes of pleural effusion and their incidence in India.  To determine the role of cytological examination of pleural fluid in diagnosis of malignant Effusion. Materials and Method: A study of 103 samples was carried out in our tertiary care teaching hospital, Ahmedabad. Samples received during june 2014 to September 2014 were examined for total count and cytology. They were also subjected to biochemical study for protein, glucose, and chloride. Results: A total 82% samples were exudative and 18% were transudative.Total leucocyte count was less than 1000cells/cumm in most (88.89%)% of transudative effusions and it was greater than 1000cells/cu.mm in 52.44% of exudative effusions.Most of the transudative effusions were secondary to cirrhosis and congestive cardiac failure.The most frequent cause of exudative effusion was tuberculosis (55.11%) followed by malignancy (28.68%), Empyema(8.89%), And pneumonia (7.32%).It was noted that 94.66% of tuberculosis effusions and more than 50% lymphocytes, 70.2% had protein greater than 5 gm/dl and 89.63% had glucose 60 mg/dl. Approximately 18 % of pleural effusions were positive for malignant cells.Most (89%) of malignant effusions were exudative. Conclusion: Pleural fluid cytology and cell count are important for knowing etiology of effusion.As compared to biopsy pleural fluid cytology is simple and relatively noninvasive technique for differentiating benign from malignant effusion.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr. Varsha Khan,Dr. R.N.Gonsai Diagnostic Value of Pleural Fluid Examination International Journal of Scientific Research, Vol : 3, Issue : 11 November 2014

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