CORRELATION OF BASELINE SERUM ALBUMIN LEVELS WITH PROGNOSIS OF GUILLAIN-BARRE SYNDROME

Shubhakaran Khichar; Amita Bhargava; Pankaj Awasthi; Ankita Bajpai

Volume : VIII, Issue : VII, July - 2019

CORRELATION OF BASELINE SERUM ALBUMIN LEVELS WITH PROGNOSIS OF GUILLAIN-BARRE SYNDROME

Shubhakaran Khichar, Amita Bhargava, Pankaj Awasthi, Ankita Bajpai

Abstract :

INTRODUCTION: Guillain–Barre syndrome (GBS) is a polyradiculoneuropathy characterized by a rapidly progressive bilateral paresis of the limbs. There is a limited number of studies in the literature which have explored the correlation between prognosis of GBS patients and serum albumin levels. So the present study was carried out.

MATERIAL AND METHODS: Prospective Longitudinal study was conducted among 60 patients admitted in the Neurology Department of MDM Hospital, Dr.SN Medical College, Jodhpur over a period of two years from January 2017 to December 2018.Serum albumin levels were determined. Patients were assigned into two groups. One with low albumin level (GROUP1) and other with normal albumin level (GROUP 2 ). And the groups were compared based on Hughe�s disability scores.

RESULTS: The albumin levels were negatively correlated with the Hughes� scores (admission/discharge). After treatment mean of the disability score in group 1 was significantly higher(p<0.05) as compared to group 2.The difference of means of disability score {end line – baseline} was significantly higher in group 1 (0.09) as compared to group 2 (–0.92).

CONCLUSION: This study determined albumin level as an independent factor for assessing the prognosis of GBS.