Volume : VII, Issue : VI, June - 2018
CONCURRENT CISPLATIN 5FU BASED CHEMOTHERAPY AND RADIOTHERAPY IN ADVANCED MUCOSAL SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Dr. K. Mahalakshmi Prasad, Dr. A. Jagadish Singh
Abstract :
One hundred and thirty four patients with locally advanced head and neck squamous cell carcinoma were prospectively studied from June 2012 –
May 2013 at Department of radiotherapy , Govt Rajaji Hospital and Madurai Medical College. All patients received concurrent Cisplatin + 5FU
based chemotherapy(CT) along with standard radiotherapy(RT).The initial complete response (CR) was 71 % and partial response was achieved in
rest 29% of the cases. The 4 yrs locoregional control was 45% for those patients who achieved complete response . Acute treatment related
toxicities included one death due to renal damage . The late toxicities noticed were xerostomia in 40% of patients. The results justify that
concomitant use of cisplatin + 5FU based chemotherapy along with radiotherapy is a effective and accepted standard of care in locally advanced
head and neck cancer patients in tertiary care centre.
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DOI : 10.36106/ijsr
Cite This Article:
DR. K.MAHALAKSHMI PRASAD, DR.A.JAGADISH SINGH, CONCURRENT CISPLATIN 5FU BASED CHEMOTHERAPY AND RADIOTHERAPY IN ADVANCED MUCOSAL SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-6 | June-2018
Number of Downloads : 187
References :
DR. K.MAHALAKSHMI PRASAD, DR.A.JAGADISH SINGH, CONCURRENT CISPLATIN 5FU BASED CHEMOTHERAPY AND RADIOTHERAPY IN ADVANCED MUCOSAL SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-6 | June-2018
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