Volume : VII, Issue : II, February - 2018
CONCURRENT CHEMORADIATION WITH SEQUENTIAL VERSUS INTERDIGITATED BRACHYTHERAPY FOR LOCALLY ADVANCED CARCINOMA CERVIX – AN OPEN LABEL RANDOMISED CLINICAL TRIAL
Dr. Abhishek Basu, Dr. Bidyut Mandal, Dr. Avik Maji, Dr. Debjit Ghosh, Prof. Dr. Swapan Kr Sikdar
Abstract :
Background
This is a prospective study to evaluate the effects of treatment duration shortening by means of Interdigitated achytherapy compå with conventional external beam radiotherapy followed by achytherapy.
Material & Methods
In study arm, The high dose rate intracavitary achytherapy using Ir192 was interdigitated from the 3rd week of EBRT, was given in 3fractions. In control arm, achy started after 1week of EBRT.
During treatment patients were reviewed weekly. After treatment completion, patients were reviewed at six weeks, then three–monthly thereafter.
Results
This study has achieved good response (96 % CR post Brachytherapy at 3 month) and local control rate (95% v/s 68% at end of follow up),which was better than sequential arm , with slightly better DFS but No OS difference.
Conclusion
Interdigitated Brachytherapy can be delivered as a standard mode of treatment in cancer cervix. Continuing this study for prolonged period and recruiting more patients will help in arriving at conclusive results
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DOI : 10.36106/ijsr
Cite This Article:
Dr. Abhishek Basu, Dr. Bidyut Mandal, Dr. Avik Maji, Dr. Debjit Ghosh, Prof. Dr. Swapan Kr Sikdar, CONCURRENT CHEMORADIATION WITH SEQUENTIAL VERSUS INTERDIGITATED BRACHYTHERAPY FOR LOCALLY ADVANCED CARCINOMA CERVIX‾AN OPEN LABEL RANDOMISED CLINICAL TRIAL, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH :
Volume-7 | Issue-2 | February-2018
Number of Downloads : 547
References :
Dr. Abhishek Basu, Dr. Bidyut Mandal, Dr. Avik Maji, Dr. Debjit Ghosh, Prof. Dr. Swapan Kr Sikdar, CONCURRENT CHEMORADIATION WITH SEQUENTIAL VERSUS INTERDIGITATED BRACHYTHERAPY FOR LOCALLY ADVANCED CARCINOMA CERVIX‾AN OPEN LABEL RANDOMISED CLINICAL TRIAL, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-2 | February-2018
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