COMPARISON OF EFFICACY OF DIFFERENT DOSES OF ROCURONIUM BROMIDE WITH SUCCINYLCHOLINE FOR RAPID SEQUENCE INTUBATION IN ADULTS

Dr. I Ravi Mohan; Dr. P. V. Phaneendra Babu; Dr. A. Anitha; Dr. K. Sridhar Reddy

Volume : VIII, Issue : VI, June - 2019

COMPARISON OF EFFICACY OF DIFFERENT DOSES OF ROCURONIUM BROMIDE WITH SUCCINYLCHOLINE FOR RAPID SEQUENCE INTUBATION IN ADULTS

Dr. I Ravi Mohan, Dr. P. V. Phaneendra Babu, Dr. A. Anitha, Dr. K. Sridhar Reddy

Abstract :

Background: Patients often require a rapid sequence induction (RSI) endotracheal intubation technique during emergencies or electively to protect against aspiration in conditions like pregnancy, abdominal pathologies especially obstruction or ileus, neurologic disease, or in difficult airway. Traditionally succinylcholine has been the most commonly used muscle relaxant for this purpose because of its fast onset and short duration; unfortunately, it can have serious side effects. Rocuronium has been suggested as an alternative to succinylcholine for intubation Methods:A study wasundertaken in Alluri Sitarama Raju Academy of Medical Sciences, during the period from July 2017 to January 2019. The patients were systematically randomized into three groupsof twenty each.Group A: Succinylcholine 1.5 mg/kg, GroupB :Rocuronium omide 0.6 mg/kg &Group C :Rocuronium omide 0.9 mg/kg.Intubating conditions, onset of action and adverse effects were observed. Results: It was observed that group A & group C patients had excellent intubation conditions with faster onset of action for group A patients. Adverse effects were not seen in any of the three groups. Conclusion: we conclude that Succinylcholine is an ideal agent for intubation in all surgical procedures. Intubating conditions of Rocuroniumomide at a dose of 0.9mg/kg(3xED95) is comparable to Succinylcholine 1.5mg/kg at1minute. Rocuroniumomide0.9mg/kgcanbe used safely in patients where succinylcholine is contraindicated.