Volume : VII, Issue : II, February - 2018
Clinical and Histological markers of poor prognosis in Acute on Chronic Liver Failure (ACLF) – An Indian perspective
Rahul Jain, Atul Jha, Kalpana Jain, Gauri Jha
Abstract :
Introduction Acute on Chronic Liver Failure (ACLF) is associated with high mortality and requires early recognition and aggressive management.
Aim To evaluate the clinical profile of ACLF and study factors associated with a poor outcome
Materials and Methods 61 cases of ACLF were e valuated. Etiological work up and Trans–jugular liver biopsy was done in all patients. Patients were followed up for a period of four weeks or till death (if earlier).
Results The mean age of patients was 40.06 +/– 4.2 years. Encephalopathy and GI Bleed was noted in 91.8% and 27.9% patients. Alcohol was the commonest etiology of chronic disease. Acute events were alcoholic hepatitis and viral hepatitis. Non–survivors had a higher incidence of GI Bleed and encephalopathy.
Conclusion ACLF is associated with alcohol and viral hepatitis. GI bleed, Hepatic encephalopathy and type I histology are associated with a poor prognosis.
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DOI : 10.36106/ijsr
Cite This Article:
Rahul Jain, Atul Jha, Kalpana Jain, Gauri Jha, Clinical and Histological markers of poor prognosis in Acute on Chronic Liver Failure (ACLF)‾An Indian perspective, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH :
Volume-7 | Issue-2 | February-2018
Number of Downloads : 232
References :
Rahul Jain, Atul Jha, Kalpana Jain, Gauri Jha, Clinical and Histological markers of poor prognosis in Acute on Chronic Liver Failure (ACLF)‾An Indian perspective, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-2 | February-2018
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