Volume : III, Issue : II, February - 2014

Changes in Liver Enzymes Following Multigenerational Exposure in Albino Rats

Jaspreet Kaur, Dr. K. S. Khera

Abstract :

Male and female albino rats were orally fed with quinalphos at dose concentration of 1mg/kg b.wt for three generations. Rats were divided into two groups i.e. control fed with peanut oil and treated fed with quinalphos for a period of six weeks in each generation to assess the alterations in the level of phosphatases and transferases in blood plasma. In male rats the ACP increased in treated rats of F0 generation whereas AKP increased in treated rats F0, F1 and F2 generation. The concentration of AST also increased in treated rats of F0 and F1 generation however the ALT increased in F0 and F2 generation. In female rats, ACP and ALP increased in F0 and F1; AST in F0 and ALT in F0 and F1 generation. Therefore the pesticide affects the basic liver enzymes when given for long term period hence altering the liver function.

Keywords :

Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Jaspreet Kaur, Dr. K. S. Khera Changes in Liver Enzymes Following Multigenerational Exposure in Albino Rats International Journal of Scientific Research, Vol.III, Issue.II February 2014

Number of Downloads : 594

References :