An Unusual Case of Synchronous Tubulocystic Renal Cell Carcinoma and Clear cell Renal Cell Carcinoma with Review of Literature

Dr. Shruti Agrawal; Dr. Nikunj Jain

Volume : IX, Issue : VIII, August - 2020

An Unusual Case of Synchronous Tubulocystic Renal Cell Carcinoma and Clear cell Renal Cell Carcinoma with Review of Literature

Dr. Shruti Agrawal, Dr. Nikunj Jain

Abstract :

Tubulocystic renal cell carcinoma (TC–RCC) is a recently described rare subtype of renal cell carcinoma (RCC) with very few cases reported in the literature until date. Reports of concurrent papillary renal cell carcinoma (PRCC) and TC‑RCC have been often documented in the literature, but the co‑occurrence of clear cell RCC (CC‑RCC) and TC‑RCC is extremely rare. We here describe a case of an incidentally detected TC‑RCC occurring with CC‑RCC in the same kidney in a 45‑year‑old male who presented with high grade fever with chills and rigors. Grossly, there were two distinct tumors in the total nephrectomy specimen. The larger tumor displayed the histopathological features of CC‑RCC and the smaller tumor revealed the features of TC‑RCC. The case report highlights the importance of having an accurate knowledge of this uncommon entity and the histomorphological differentiation from the more common renal neoplasms.