Volume : IV, Issue : VI, June - 2015

ALK– NEGATIVE, ANAPLASTIC LARGE CELL LYMPHOMA– A CASE REPORT

Dr. Sujata. S. Giriyan, Dr. Kiran. S. M.

Abstract :

 Anaplastic large cell lymphoma (ALCL), Anaplastic lymphoma kinase (ALK)–negative (ALCL–ALK−) is a provisional entity in the WHO 2008 Classification that represents 2–3% of NHL and 12% of T–cell NHL. Patients with ALCL–ALK− are usually adults with a median age of 54–61 years, and a male–to–female ratio of 0.9. ALCL–ALK− presents with lymph node involvement in ∼50% of cases; extranodal spread (20%) is less common. Staging work–up for ALCL–ALK− is similar to that routinely used for nodal NHL. Overall prognosis is poor, with a 5–year of 30–49%, which is significantly worse when compared to reported in patients with ALCL–ALK+ (5–year: 70–86%)5.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr.Sujata.S.Giriyan, Dr. Kiran.S.M. Alk- Negative, Anaplastic Large Cell Lymphoma- A Case Report International Journal of Scientific Research, Vol : 4, Issue : 6 June 2015

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